Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02ADC
|
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| Former ID |
DIB010216
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| Drug Name |
SDZ-MKS-492
|
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| Synonyms |
MKS-492
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| Drug Type |
Small molecular drug
|
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| Company |
Novartis AG
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| Structure |
|
Download2D MOL |
|||
| Formula |
C20H27N5O6
|
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| Canonical SMILES |
c12c(c(=O)n(c(=O)n2C)C)n(c(n1)N[C@H](c1cc(c(cc1)OC)OC)C<br />O)CCOC
|
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| CAS Number |
CAS 114606-56-3
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Phosphodiesterase (PDE) 3 | Target Info | Modulator | [533607], [533957] | |
| References | |||||
| Ref 533607 | Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats. Jpn J Pharmacol. 1993 Dec;63(4):405-13. | ||||
| Ref 533957 | Effects of a cyclic nucleotide phosphodiesterase isoenzyme type III inhibitor, SDZ MKS 492 on airway responsiveness in beagles. Arerugi. 1993 Aug;42(8):920-5. | ||||
| Ref 533607 | Effects of MKS-492 on antigen-induced bronchoconstriction and allergic reaction in guinea pigs and rats. Jpn J Pharmacol. 1993 Dec;63(4):405-13. | ||||
| Ref 533957 | Effects of a cyclic nucleotide phosphodiesterase isoenzyme type III inhibitor, SDZ MKS 492 on airway responsiveness in beagles. Arerugi. 1993 Aug;42(8):920-5. | ||||
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