Drug Information

Drug General Information
Drug ID
D02DJR
Former ID
DNCL001622
Drug Name
AMG 167
Indication Osteopenia [ICD9: 733.9; ICD10:M85.8] Phase 1 [523001]
Company
Amgen Thousand
Target and Pathway
Target(s) Sclerostin Target Info Modulator [544316]
KEGG Pathway Wnt signaling pathway
NetPath Pathway TWEAK Signaling Pathway
Reactome TCF dependent signaling in response to WNT
Negative regulation of TCF-dependent signaling by WNT ligand antagonists
References
Ref 523001ClinicalTrials.gov (NCT01101048) An Ascending Multiple Dose Study Evaluating AMG 167 in Healthy Men and Postmenopausal Women With Low Bone Mineral Density. U.S. National Institutes of Health.
Ref 544316Osteoporosis - a current view of pharmacological prevention and treatment. Drug Des Devel Ther. 2013; 7: 435-448.

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