Drug General Information
Drug ID	D02EPZ
Former ID	DNC005056
Drug Name	2-(2,6-Dimethyl-benzyl)-4,5-dihydro-1H-imidazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[527180]
Structure		Download 2D MOL 3D MOL
Formula	C12H16N2
Canonical SMILES	CC1=C(C(=CC=C1)C)CC2=NCCN2
InChI	1S/C12H16N2/c1-9-4-3-5-10(2)11(9)8-12-13-6-7-14-12/h3-5H,6-8H2,1-2H3,(H,13,14)
InChIKey	GPUVYOKQAJEFBO-UHFFFAOYSA-N
PubChem Compound ID	24782016
Target and Pathway
Target(s)	5-hydroxytryptamine 1D receptor	Target Info	Inhibitor	[527180]
KEGG Pathway	cAMP signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	5HT1 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (i) signalling events
WikiPathways	Serotonin HTR1 Group and FOS Pathway
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 527180	Bioorg Med Chem Lett. 2004 Sep 20;14(18):4697-9.2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands.
Ref 527180	Bioorg Med Chem Lett. 2004 Sep 20;14(18):4697-9.2-(Anilino)imidazolines and 2-(benzyl)imidazoline derivatives as h5-HT1D serotonin receptor ligands.

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