Drug General Information
Drug ID	D02ESW
Drug Name	MK-212
Synonyms	64022-27-1; MK-212
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1559573], [1559717]
Structure		Download 2D MOL 3D MOL
Formula	C8H11ClN4
PubChem Compound ID	107992
Target and Pathway
Target(s)	5-hydroxytryptamine 2C receptor	Target Info	Modulator
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Gap junction
	Serotonergic synapse
	Inflammatory mediator regulation of TRP channels
PANTHER Pathway	5HT2 type receptor mediated signaling pathway
Reactome	Serotonin receptors
	G alpha (q) signalling events
WikiPathways	Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1559573	[Agonists of 5HT2C-receptors SCH 23390 and MK 212 incresase the force of rat aorta contraction in the presence of vasopressin and angiotensin II].Patol Fiziol Eksp Ter.2014 Oct-Dec;(4):17-29.
Ref 1559717	Effects of 5-hydroxytryptamine 2C receptor agonist MK212 and 2A receptor antagonist MDL100907 on maternal behavior in postpartum female rats.Pharmacol Biochem Behav.2014 Feb;117:25-33.

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