Drug Information

Drug General Information
Drug ID
D02EZM
Former ID
DNAP001689
Drug Name
Fospropofol disodium
Synonyms
Lusedra (TN)
Drug Type
Small molecular drug
Indication Monitored anaesthesia care sedation [ICD9: 338; ICD10:R52, G89] Approved [526010], [529941]
Company
Eisai
Structure
Download
2D MOL

3D MOL
Formula
C13H19Na2O5P
Canonical SMILES
CC(C)C1=C(C(=CC=C1)C(C)C)OCOP(=O)([O-])[O-].[Na+].[Na+]
InChI
1S/C13H21O5P.2Na/c1-9(2)11-6-5-7-12(10(3)4)13(11)17-8-18-19(14,15)16;;/h5-7,9-10H,8H2,1-4H3,(H2,14,15,16);;/q;2*+1/p-2
InChIKey
LWYLQNWMSGFCOZ-UHFFFAOYSA-L
CAS Number
CAS 258516-87-9
PubChem Compound ID
3038497
PubChem Substance ID
10049036, 14777544, 22395212, 36106210, 47206198, 50075292, 51256489, 57353733, 111646214, 126667077, 135141574, 144238881, 160699489, 160967885, 172913875, 175266449, 223666244, 241325338
SuperDrug ATC ID
N01AX10
Target and Pathway
Target(s) Glutamate receptor AMPA subtype Target Info Modulator [551871]
References
Ref 526010General anesthetic potencies of a series of propofol analogs correlate with potency for potentiation of gamma-aminobutyric acid (GABA) current at the GABA(A) receptor but not with lipid solubility. JPharmacol Exp Ther. 2001 Apr;297(1):338-51.
Ref 5299412008 FDA drug approvals. Nat Rev Drug Discov. 2009 Feb;8(2):93-6.
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015

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