Drug Information

Drug General Information
Drug ID
D02GLD
Former ID
DIB008204
Drug Name
MF-101
Synonyms
Liquiritigenin; Menerba; DW-700; DW-700); Menopause Formula-101; Estrogen receptor beta agonist (menopausal symptoms), Bionovo; Liquiritigenin (menopausal symptoms), Bionovo
Indication Hepatitis virus infection [ICD9: 573.3; ICD10:K75.9] Phase 3 [522672]
Company
Bionovo Inc; Daewon Pharm Co Ltd
Structure
Download
2D MOL

3D MOL
Canonical SMILES
c12c(C(=O)C[C@H](O1)c1ccc(cc1)O)ccc(c2)O
CAS Number
CAS 578-86-9
Target and Pathway
Target(s) Estrogen receptor beta Target Info Antagonist [529943]
KEGG Pathway Estrogen signaling pathway
Prolactin signaling pathway
Pathway Interaction Database Plasma membrane estrogen receptor signaling
Validated nuclear estrogen receptor beta network
Validated nuclear estrogen receptor alpha network
Reactome Nuclear Receptor transcription pathway
WikiPathways SIDS Susceptibility Pathways
Ovarian Infertility Genes
Integrated Pancreatic Cancer Pathway
Nuclear Receptors
References
Ref 522672ClinicalTrials.gov (NCT00906308) A Study of MF101 in Postmenopausal Women. U.S. National Institutes of Health.
Ref 529943MF101, a selective estrogen receptor beta modulator for the treatment of menopausal hot flushes: a phase II clinical trial. Menopause. 2009 May-Jun;16(3):458-65.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.