Drug General Information
Drug ID	D02HEK
Former ID	DNC011526
Drug Name	1-(9H-beta-Carbolin-3-yl)-ethanone
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533414]
Structure		Download 2D MOL 3D MOL
Formula	C13H10N2O
Canonical SMILES	CC(=O)C1=NC=C2C(=C1)C3=CC=CC=C3N2
InChI	1S/C13H10N2O/c1-8(16)12-6-10-9-4-2-3-5-11(9)15-13(10)7-14-12/h2-7,15H,1H3
InChIKey	MPLXFBXMWYMAFN-UHFFFAOYSA-N
PubChem Compound ID	12789146
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533414]
	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533414]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533414	J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.
Ref 533414	J Med Chem. 1987 Apr;30(4):750-3.Synthesis of 6-substituted beta-carbolines that behave as benzodiazepine receptor antagonists or inverse agonists.

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