TTD | Drug: D02HRB

Drug General Information
Drug ID	D02HRB
Former ID	DNC011678
Drug Name	RWJ-16979
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[533762]
Structure		Download 2D MOL 3D MOL
Formula	C18H15N3O2
Canonical SMILES	C1CN2C3=CC=CC=C3NC2=C(C1=O)C(=O)NC4=CC=CC=C4
InChI	1S/C18H15N3O2/c22-15-10-11-21-14-9-5-4-8-13(14)20-17(21)16(15)18(23)19-12-6-2-1-3-7-12/h1-9,20H,10-11H2,(H,19,23)
InChIKey	AOXBTUWPBDHMSU-UHFFFAOYSA-N
PubChem Compound ID	11722634
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[533762]
Target(s)	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[533762]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
Reactome	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 533762	J Med Chem. 1995 Jan 6;38(1):16-20.Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors.
Ref 533762	J Med Chem. 1995 Jan 6;38(1):16-20.Potential anxiolytic agents. Pyrido[1,2-a]benzimidazoles: a new structural class of ligands for the benzodiazepine binding site on GABA-A receptors.

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Drug Information