Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02KKQ
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| Former ID |
DIB008462
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| Drug Name |
BAM-1110
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| Synonyms |
(6aR,9R,10aR)-7-Methyl-9-(1,2,4-triazol-1-ylmethyl)-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinolinemaleate
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| Drug Type |
Small molecular drug
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| Indication | Parkinson's disease [ICD9: 332; ICD10:G20] | Discontinued in Phase 2 | [545888] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C18H21N5
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| Canonical SMILES |
CN1CC(CC2C1CC3=CNC4=CC=CC2=C34)CN5C=NC=N5
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| InChI |
1S/C18H21N5/c1-22-8-12(9-23-11-19-10-21-23)5-15-14-3-2-4-16-18(14)13(7-20-16)6-17(15)22/h2-4,7,10-12,15,17,20H,5-6,8-9H2,1H3/t12-,15?,17-/m1/s1
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| InChIKey |
AIBHLZVVPXCTKY-XURPUJGUSA-N
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Dopamine D1 receptor | Target Info | Modulator | ||
| D(2) dopamine receptor | Target Info | Modulator | |||
| PANTHER Pathway | Dopamine receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Dopamine receptor mediated signaling pathway | |||||
| Nicotine pharmacodynamics pathway | |||||
| PathWhiz Pathway | Dopamine Activation of Neurological Reward System | ||||
| WikiPathways | Hypothetical Network for Drug Addiction | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Genes and (Common) Pathways Underlying Drug Addiction | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP666:Hypothetical Network for Drug Addiction | |||||
| GPCR downstream signaling | |||||
| Nicotine Activity on Dopaminergic Neurons | |||||
| References | |||||
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