Drug Information

Drug General Information
Drug ID
D02LUF
Former ID
DNC009191
Drug Name
(+)-(5S,8S,10S)-20-methoxy-9,15-ene-puupehenol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526556]
Structure
Download
2D MOL

3D MOL
Formula
C21H28O3
Canonical SMILES
CC1(CCCC2(C1CCC3C2=CC4=CC(=C(C=C4O3)O)OC)C)C
InChI
1S/C21H28O3/c1-20(2)8-5-9-21(3)14-10-13-11-18(23-4)15(22)12-17(13)24-16(14)6-7-19(20)21/h10-12,16,19,22H,5-9H2,1-4H3/t16-,19-,21+/m0/s1
InChIKey
VKVKDSPLZVAEMG-NBHGPNQESA-N
PubChem Compound ID
44584373
Target and Pathway
Target(s) Arachidonate 15-lipoxygenase Target Info Inhibitor [526556]
Arachidonate 12-lipoxygenase, 12S-type Target Info Inhibitor [526556]
BioCyc Pathway Resolvin D biosynthesis
Lipoxin biosynthesisPWY66-392:Lipoxin biosynthesis
KEGG Pathway Arachidonic acid metabolism
Linoleic acid metabolism
Metabolic pathways
Serotonergic synapsehsa00590:Arachidonic acid metabolism
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL4 Signaling Pathway
PANTHER Pathway Inflammation mediated by chemokine and cytokine signaling pathwayP00031:Inflammation mediated by chemokine and cytokine signaling pathway
Pathway Interaction Database IL4-mediated signaling events
PathWhiz Pathway Arachidonic Acid MetabolismPW000044:Arachidonic Acid Metabolism
WikiPathways Arachidonic acid metabolism
Eicosanoid SynthesisWP2650:Arachidonic acid metabolism
Eicosanoid Synthesis
References
Ref 526556J Nat Prod. 2003 Feb;66(2):230-5.Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.
Ref 526556J Nat Prod. 2003 Feb;66(2):230-5.Exploring sponge-derived terpenoids for their potency and selectivity against 12-human, 15-human, and 15-soybean lipoxygenases.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.