Drug Information

Drug General Information
Drug ID
D02MST
Former ID
DIB018635
Drug Name
5-(nonyloxy)-tryptamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [538643]
Structure
Download
2D MOL
Formula
C19H30N2O
InChI
InChI=1S/C19H30N2O/c1-2-3-4-5-6-7-8-13-22-17-9-10-19-18(14-17)16(11-12-20)15-21-19/h9-10,14-15,21H,2-8,11-13,20H2,1H3
InChIKey
YHSMSRREJYOGQJ-UHFFFAOYSA-N
PubChem Compound ID
1797
PubChem Substance ID
5244805, 8151290, 11113772, 14776228, 26751955, 29220996, 47217007, 47440494, 57321029, 74606294, 85209666, 85789470, 103142531, 103309415, 103947142, 104298749, 117534335, 129797481, 134340944, 135088539, 135610592, 135649844, 137054299, 162219823, 162797793, 179236163, 184590372, 228455448, 245050255
Target and Pathway
Target(s) 5-hydroxytryptamine 1B receptor Target Info Agonist [525602]
KEGG Pathway cAMP signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
5HT1 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Serotonin HTR1 Group and FOS Pathway
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 538643(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 106).
Ref 525602Identification of an amino acid residue important for binding of methiothepin and sumatriptan to the human 5-HT(1B) receptor. Eur J Pharmacol. 1999 Sep 10;380(2-3):171-81.

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