TTD | Drug: D02NZI

Drug General Information
Drug ID	D02NZI
Former ID	DIB020962
Drug Name	SM-130,686
Synonyms	SM 130686
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[541175]
Structure		Download 2D MOL 3D MOL
Formula	C22H23ClF3N3O3
InChI	InChI=1S/C22H23ClF3N3O3/c1-3-28(4-2)9-10-29-17-12-13(19(27)30)11-15(22(24,25)26)18(17)21(32,20(29)31)14-7-5-6-8-16(14)23/h5-8,11-12,32H,3-4,9-10H2,1-2H3,(H2,27,30)/t21-/m1/s1
InChIKey	YSSPGXCFFITNCE-OAQYLSRUSA-N
PubChem Compound ID	9804743
PubChem Substance ID	14760855, 24112831, 44840740, 79091072, 103445641, 104039434, 141830015, 142934208, 178102490, 232105523, 244891561
Target and Pathway
Target(s)	Growth hormone secretagogue receptor type 1	Target Info	Agonist	[526224]
KEGG Pathway	cAMP signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	Leptin Signaling Pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 541175	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5866).
Ref 526224	Oxindole derivatives as orally active potent growth hormone secretagogues. J Med Chem. 2001 Dec 20;44(26):4641-9.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.

Drug Information