Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02OJC
|
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| Former ID |
DCL000663
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| Drug Name |
Xaliproden
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| Synonyms |
Xaliproden (USAN); 1,2,3,6-tetrahydro-1-(2-(2-naphthalenyl)ethyl)-4-(3-(trifluoromethyl)phenyl)-pyridine; 1,2,3,6-tetrahydro-1-(2-(2-naphthyl)ethyl)-4-(alpha,alpha,alpha-trifluoro-m-tolyl)pyridine; 1-(2-(2-Naphthyl)ethyl)-4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine; 1-(2-naphthalen-2-ylethyl)-4-[3-(trifluoromethyl)phenyl]-3,6-dihydro-2H-pyridine; 1-[2-(2-naphthyl)ethyl]-4-[3-(trifluoromethyl)phenyl]-1,2,3,6-tetrahydropyridine
|
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| Drug Type |
Small molecular drug
|
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| Indication | Alzheimer disease; Peripheral sensory neuropathies; Lateral sclerosis [ICD9: 331.0, 356.0, 356.8; ICD10:G30, G64, G90.0, G12.2] | Discontinued in Phase 3 | [544941] | ||
| Company |
Sanofi-Aventis
|
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| Structure |
|
Download2D MOL |
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| Formula |
C24H22F3N
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| Canonical SMILES |
C1CN(CC=C1C2=CC(=CC=C2)C(F)(F)F)CCC3=CC4=CC=CC=C4C=C3
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| InChI |
1S/C24H22F3N/c25-24(26,27)23-7-3-6-22(17-23)20-11-14-28(15-12-20)13-10-18-8-9-19-4-1-2-5-21(19)16-18/h1-9,11,16-17H,10,12-15H2
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| InChIKey |
WJJYZXPHLSLMGE-UHFFFAOYSA-N
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| CAS Number |
CAS 428863-50-7
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| SuperDrug ATC ID |
N07XX03
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| SuperDrug CAS ID |
cas=135354028
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| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 1A receptor | Target Info | Antagonist | [549823] | |
| References | |||||
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