Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02TIK
|
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| Former ID |
DCL000837
|
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| Drug Name |
HP-184
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| Synonyms |
Nerispirdine; Nerispirdine hydrochloride; HP 184; N-(3-fluoropyridin-4-yl)-3-methyl-N-propylindol-1-amine; N-(n-Propyl)-3-fluoro-4-pyridinyl-1H-3-methylindol-1-amine hydrochloride; N-(3-Fluoro-4-pyridinyl)-3-methyl-N-propyl-1H-indol-1-amine; 1H-Indol-1-amine, N-(3-fluoro-4-pyridinyl)-3-methyl-N-propyl-, monohydrochloride
|
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| Drug Type |
Small molecular drug
|
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| Indication | Multiple scierosis [ICD9: 340; ICD10:G35] | Phase 2 | [536648] | ||
| Company |
Sanofi-Aventis
|
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| Structure |
|
Download2D MOL |
|||
| Formula |
C17H18FN3
|
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| Canonical SMILES |
CCCN(C1=C(C=NC=C1)F)N2C=C(C3=CC=CC=C32)C
|
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| InChI |
1S/C17H18FN3/c1-3-10-20(17-8-9-19-11-15(17)18)21-12-13(2)14-6-4-5-7-16(14)21/h4-9,11-12H,3,10H2,1-2H3
|
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| InChIKey |
BTDHTARYCBHHPJ-UHFFFAOYSA-N
|
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| CAS Number |
CAS 119229-65-1
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Potassium voltage-gated channel subfamily H member 2 | Target Info | Blocker | [536648] | |
| Voltage-gated sodium channel | Target Info | Blocker | [536648] | ||
| PathWhiz Pathway | Muscle/Heart Contraction | ||||
| Reactome | Voltage gated Potassium channels | ||||
| References | |||||
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