Drug General Information
Drug ID	D02UCT
Former ID	DNC001192
Drug Name	R-820
Indication	Discovery agent		Investigative	[535700]
Structure		Download 2D MOL 3D MOL
Formula	O2Ti
CAS Number	CAS 98084-96-9
Target and Pathway
Target(s)	Nigral tachykinin NK(3) receptor	Target Info	Antagonist	[535700]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
Reactome	G alpha (q) signalling events
WikiPathways	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 535700	Implication of nigral tachykinin NK3 receptors in the maintenance of hypertension in spontaneously hypertensive rats: a pharmacologic and autoradiographic study. Br J Pharmacol. 2003 Feb;138(4):554-63.
Ref 535700	Implication of nigral tachykinin NK3 receptors in the maintenance of hypertension in spontaneously hypertensive rats: a pharmacologic and autoradiographic study. Br J Pharmacol. 2003 Feb;138(4):554-63.

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