Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D02YSX
|
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| Former ID |
DNC010278
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| Drug Name |
DIMEBOLIN
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [530547] | ||
| Structure |
|
Download2D MOL |
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| Formula |
C21H25N3
|
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| Canonical SMILES |
CC1=CC2=C(C=C1)N(C3=C2CN(CC3)C)CCC4=CN=C(C=C4)C
|
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| InChI |
1S/C21H25N3/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17/h4-7,12-13H,8-11,14H2,1-3H3
|
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| InChIKey |
JNODQFNWMXFMEV-UHFFFAOYSA-N
|
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | 5-hydroxytryptamine 6 receptor | Target Info | Inhibitor | [530540] | |
| Histamine H1 receptor | Target Info | Inhibitor | [530547] | ||
| PathWhiz Pathway | Excitatory Neural Signalling Through 5-HTR 6 and Serotonin | ||||
| References | |||||
| Ref 530540 | Eur J Med Chem. 2010 Feb;45(2):782-9. Epub 2009 Oct 31.8-Sulfonyl-substituted tetrahydro-1H-pyrido[4,3-b]indoles as 5-HT6 receptor antagonists. | ||||
| Ref 530547 | Bioorg Med Chem Lett. 2010 Jan 1;20(1):78-82. Epub 2009 Nov 14.Synthesis and biological activity of 5-styryl and 5-phenethyl-substituted 2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indoles. | ||||
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