Drug Information

Drug General Information
Drug ID
D02YXQ
Former ID
DNC011713
Drug Name
GT-2016
Drug Type
Small molecular drug
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Terminated [545044]
Structure
Download
2D MOL

3D MOL
Formula
C19H31N3O
Canonical SMILES
C1CCC(CC1)CCCCC(=O)N2CCC(CC2)C3=CN=CN3
InChI
1S/C19H31N3O/c23-19(9-5-4-8-16-6-2-1-3-7-16)22-12-10-17(11-13-22)18-14-20-15-21-18/h14-17H,1-13H2,(H,20,21)
InChIKey
YTCGNPGLMAECND-UHFFFAOYSA-N
PubChem Compound ID
9839975
Target and Pathway
Target(s) Histamine H3 receptor Target Info Inhibitor [534790]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 545044Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001957)
Ref 534790Bioorg Med Chem Lett. 1998 May 19;8(10):1133-8.New acetylene based histamine H3 receptor antagonists derived from the marine natural product verongamine.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.