Drug Information

Drug General Information
Drug ID
D02ZCP
Former ID
DNC002967
Drug Name
5-Phenylsulfanyl-2,4-Quinazolinediamine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [551393]
Structure
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2D MOL

3D MOL
Formula
C14H12N4S
Canonical SMILES
C1=CC=C(C=C1)SC2=CC=CC3=C2C(=NC(=N3)N)N
InChI
1S/C14H12N4S/c15-13-12-10(17-14(16)18-13)7-4-8-11(12)19-9-5-2-1-3-6-9/h1-8H,(H4,15,16,17,18)
InChIKey
BUFDQCGCADQQQY-UHFFFAOYSA-N
PubChem Compound ID
446244
PubChem Substance ID
614493, 822542, 4502316, 7890859, 10299857, 36888718, 46506958, 46518161, 80774600, 85861052, 103315288, 103855308, 104636078, 127568831, 134349911, 137184798, 142351645, 160967219, 180086067, 228262213
Target and Pathway
Target(s) Dihydrofolate reductase Target Info Inhibitor [551393]
PathWhiz Pathway Folate Metabolism
Pterine Biosynthesis
Reactome E2F mediated regulation of DNA replication
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Metabolism of folate and pterines
G1/S-Specific Transcription
References
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
Ref 551393How many drug targets are there? Nat Rev Drug Discov. 2006 Dec;5(12):993-6.

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