TTD | Drug: D03AZU

Drug General Information
Drug ID	D03AZU
Former ID	DIB016114
Drug Name	Org-31710
Synonyms	Org-31806
Drug Type	Small molecular drug
Indication	Contraception [ICD10:Z30]		Discontinued in Phase 1	[545237]
Company	Organon BioSciences
Structure		Download 2D MOL 3D MOL
Formula	C30H39NO2
Canonical SMILES	C12=C3C(=CC(=O)CC3)[C@@H](C[C@H]1[C@H]1[C@](C[C@@H]2c2c<br />cc(N(C)C)cc2)([C@@]2(OCCC2)CC1)C)C
PubChem Compound ID	164090
Target and Pathway
Target(s)	Progesterone receptor	Target Info	Modulator	[526214]
KEGG Pathway	Oocyte meiosis
KEGG Pathway	Progesterone-mediated oocyte maturation
Pathway Interaction Database	Cellular roles of Anthrax toxin
Reactome	Nuclear signaling by ERBB4
Reactome	Nuclear Receptor transcription pathway
WikiPathways	Ovarian Infertility Genes
	Signaling by ERBB4
	Nuclear Receptors
References
Ref 545237	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002550)
Ref 526214	Progesterone receptor antagonists Org 31710 and RU 486 increase apoptosis in human periovulatory granulosa cells. Fertil Steril. 2001 Dec;76(6):1225-31.

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Drug Information