Drug General Information
Drug ID	D03AZY
Former ID	DCL000934
Drug Name	PNU-177864
Indication	Schizophrenia [ICD9: 295; ICD10:F20]		Terminated	[536463]
Company	Pfizer
Structure		Download 2D MOL
Target and Pathway
Target(s)	D(3) dopamine receptor	Target Info	Antagonist	[536463]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Dopaminergic synapse
Reactome	Dopamine receptors
	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
	Nicotine Activity on Dopaminergic Neurons
	GPCRs, Other
References
Ref 536463	The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.
Ref 536463	The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. Epub 2007 Jul 31.

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