TTD | Drug: D03BGG

Drug General Information
Drug ID	D03BGG
Former ID	DIB015691
Drug Name	ST-1141
Synonyms	Ghrelin agonist (oral, opioid-induced bowel dysfunction), Helsinn
Indication	Functional bowel disorder [ICD10:K00-K93]		Phase 1	[548492]
Company	Sapphire Therapeutics Inc
Target and Pathway
Target(s)	Growth hormone secretagogue receptor type 1	Target Info	Agonist	[550985]
KEGG Pathway	cAMP signaling pathway
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	Leptin Signaling Pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (q) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 548492	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800025998)
Ref 550985	The Prokinetic Face of Ghrelin. International Journal of Peptides Volume 2010 (2010), Article ID 493614, Page(11).

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Drug Information