Drug Information

Drug General Information
Drug ID
D03CWX
Former ID
DIB007708
Drug Name
MEM-1414
Synonyms
R-1533; PDE 4 inhibitor (Alzheimer's), Memory; PDE 4 inhibitor (Alzheimer's), Memory/Roche
Indication Mood disorder [ICD10:F30-F39] Phase 1 [551843]
Company
Memory Pharmaceuticals Corp
Target and Pathway
Target(s) CAMP-specific 3',5'-cyclic phosphodiesterase 4B Target Info Inhibitor [533010]
Type IV phosphodiesterase Target Info Inhibitor [533010]
CAMP-specific 3',5'-cyclic phosphodiesterase 4A Target Info Inhibitor [533010]
KEGG Pathway Purine metabolism
cAMP signaling pathway
Morphine addictionhsa00230:Purine metabolism
Morphine addiction
NetPath Pathway IL5 Signaling Pathway
IL2 Signaling Pathway
PathWhiz Pathway Purine Metabolism
Reactome DARPP-32 events
G alpha (s) signalling eventsR-HSA-180024:DARPP-32 events
G alpha (s) signalling events
WikiPathways G Protein Signaling Pathways
Myometrial Relaxation and Contraction Pathways
Nuclear Receptors Meta-Pathway
Opioid SignallingWP35:G Protein Signaling Pathways
TSH signaling pathwayWP35:G Protein Signaling Pathways
References
Ref 551843The Quest for Human Longevity, Lewis D. Solo. Page(145).
Ref 533010The effect of the novel phosphodiesterase-4 inhibitor MEM 1414 on the allergen induced responses in mild asthma. BMC Pulm Med. 2014 Oct 28;14:166.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.