Drug Information

Drug General Information
Drug ID
D03FLC
Former ID
DAP000039
Drug Name
Lamotrigine
Synonyms
Crisomet; Labileno; Lamictal; Lamictin; Lamiktal; Lamitor; Lamotrigina; Lamotriginum; Desitin Brand of Lamotrigine; Faes Brand of Lamotrigine; Glaxo Wellcome Brand of Lamotrigine; GlaxoSmithKline Brand of Lamotrigine; Juste Brand of Lamotrigine; Lamictal Cd; Lamictal ODT; Lamictal XR; Lamotrigina [Spanish]; Lamotriginum [Latin]; BW 430C; GI 267119X; GW 273293; L 3791; BW-430C; EUR-1048; Lamictal (TN); Lamictin (TN); Lamotrigine [USAN:INN:BAN]; Lamotrigine (JAN/USAN/INN); 3,5-Diamino-6-(2,3-dichlorophenyl)-1,2,4-triazine; 3,5-Diamino-6-(2,3-dichlorophenyl)-as-triazine; 3,5-diamino-6-(2,3-dichlorophenyl)-as-triazine; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diamine; 6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diyldiamine; 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
Drug Type
Small molecular drug
Indication Epilepsy; Bipolar disorder [ICD9: 296, 345; ICD10:F31, G40] Approved [536756], [539692]
Therapeutic Class
Anticonvulsants
Company
GSK
Structure
Download
2D MOL

3D MOL
Formula
C9H7Cl2N5
InChI
InChI=1S/C9H7Cl2N5/c10-5-3-1-2-4(6(5)11)7-8(12)14-9(13)16-15-7/h1-3H,(H4,12,13,14,16)
InChIKey
PYZRQGJRPPTADH-UHFFFAOYSA-N
CAS Number
CAS 84057-84-1
PubChem Compound ID
3878
PubChem Substance ID
855818, 5669156, 7847420, 7979720, 8152444, 11111377, 11113342, 11528749, 12013463, 14823602, 17405249, 24278792, 26719658, 29222992, 46386680, 46505408, 47810853, 48259345, 48416154, 50100261, 50104089, 50104090, 53777794, 53787568, 56423136, 57322032, 58107296, 76843584, 81092819, 85231112, 90341162, 91148150, 92304062, 92308151, 92308280, 92308924, 92709766, 93166952, 103199382, 103940000, 104179107, 104304778, 111978157, 117872151, 121361621, 124658861, 124799528, 124880544, 124880545, 124880546
SuperDrug ATC ID
N03AX09
SuperDrug CAS ID
cas=084057841
Target and Pathway
Target(s) Voltage-gated sodium channel Target Info Blocker [537583]
References
Ref 536756Use of second-generation antiepileptic drugs in the pediatric population. Paediatr Drugs. 2008;10(4):217-54.
Ref 539692(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2622).
Ref 537583The effects of lamotrigine on the acquisition and expression of morphine-induced place preference in mice. Pak J Biol Sci. 2009 Jan 1;12(1):33-9.

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