Drug General Information
Drug ID
D03GPH
Former ID
DNC014622
Drug Name
1-(4-Chloro-phenyl)-3-(3-pentyl-oct-2-enyl)-urea
Drug Type
Small molecular drug
Indication Discovery agent Investigative [527275]
Structure
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2D MOL

3D MOL

Formula
C20H31ClN2O
Canonical SMILES
CCCCCC(=CCNC(=O)NC1=CC=C(C=C1)Cl)CCCCC
InChI
1S/C20H31ClN2O/c1-3-5-7-9-17(10-8-6-4-2)15-16-22-20(24)23-19-13-11-18(21)12-14-19/h11-15H,3-10,16H2,1-2H3,(H2,22,23,24)
InChIKey
CIWRUSYLNXXOOQ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Inhibitor [527275]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 527275J Med Chem. 1992 Mar 20;35(6):1042-9.Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718.
Ref 527275J Med Chem. 1992 Mar 20;35(6):1042-9.Hybrid cholecystokinin-A antagonists based on molecular modeling of lorglumide and L-364,718.

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