Drug Information

Drug General Information
Drug ID
D03IDK
Former ID
DIB002091
Drug Name
CEP-18050
Synonyms
ALK inhibitors (anaplastic large cell lymphoma); CEP-18050; ALK inhibitors (anaplastic large cell lymphoma), Cephalon; Alk inhibitors (cancer), Cephalon
Indication Lymphoma [ICD9: 202.8, 208.9; ICD10:C81-C86] Investigative [543509]
Company
Cephalon Inc
Structure
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2D MOL

3D MOL
Canonical SMILES
c1c(c(cc2c1CCN(CC2)CC(=O)N(C)C)OC)Nc1nc(c(cn1)Cl)Nc1c(c<br />c(cc1)N1CCOCC1)OC
Target and Pathway
Target(s) ALK tyrosine kinase receptor Target Info Inhibitor [543509]
KEGG Pathway Non-small cell lung cancer
WikiPathways Differentiation Pathway
References
Ref 543509(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1839).
Ref 543509(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 1839).

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