Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03JCA
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| Former ID |
DIB003870
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| Drug Name |
MB-11055
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| Synonyms |
Cryptotanshinone, MD BioAlpha; Cryptotanshinone, Mazence; AMP activated protein kinase stimulator (liver cirrhosis/steatosis/steatohepatitis), Mazence; AMPK stimulator (liver cirrhosis/steatosis/steatohepatitis), Mazence; Lipid metabolism stimulator (liver cirrhosis/steatosis/steatohepatitis), Mazence
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| Indication | Fatty liver disease [ICD10:K70, K76.0] | Phase 2 | [549310] | ||
| Company |
Mazence Inc
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| Structure |
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Download2D MOL |
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| Canonical SMILES |
C[C@H]1COC2=C1C(=O)C(=O)c3c4CCCC(C)(C)c4ccc23
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| InChI |
1S/C19H20O3/c1-10-9-22-18-12-6-7-13-11(5-4-8-19(13,2)3)15(12)17(21)16(20)14(10)18/h6-7,10H,4-5,8-9H2,1-3H3/t10-/m0/s1
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| InChIKey |
GVKKJJOMQCNPGB-JTQLQIEISA-N
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| Target and Pathway | |||||
| Target(s) | AMP-activated protein kinase | Target Info | Modulator | ||
| KEGG Pathway | FoxO signaling pathway | ||||
| Regulation of autophagy | |||||
| mTOR signaling pathway | |||||
| PI3K-Akt signaling pathway | |||||
| AMPK signaling pathway | |||||
| Circadian rhythm | |||||
| Insulin signaling pathway | |||||
| Adipocytokine signaling pathway | |||||
| Oxytocin signaling pathway | |||||
| Glucagon signaling pathway | |||||
| Non-alcoholic fatty liver disease (NAFLD) | |||||
| Hypertrophic cardiomyopathy (HCM) | |||||
| References | |||||
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