Drug General Information
Drug ID
D03JIH
Former ID
DIB002560
Drug Name
SSR-125180
Indication Obesity [ICD9: 278; ICD10:E66] Discontinued in Phase 1 [547405]
Company
Sanofi-Synthelabo
Target and Pathway
Target(s) Cholecystokinin receptor type A Target Info Agonist [550839]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Insulin secretion
Pancreatic secretion
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
Peptide GPCRs
GPCR ligand binding
GPCR downstream signaling
References
Ref 547405Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800015967)
Ref 550839US patent application no. 8,748,419, Antagonists.

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