Drug Information

Drug General Information
Drug ID
D03NKE
Former ID
DNC009450
Drug Name
6-bromo-2'-de-N-methylaplysinopsin
Drug Type
Small molecular drug
Indication Discovery agent Investigative [526321]
Structure
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2D MOL

3D MOL
Formula
C13H11BrN4O
Canonical SMILES
CN1C(=O)C(=CC2=CNC3=C2C=CC(=C3)Br)N=C1N
InChI
1S/C13H11BrN4O/c1-18-12(19)11(17-13(18)15)4-7-6-16-10-5-8(14)2-3-9(7)10/h2-6,16H,1H3,(H2,15,17)/b11-4+
InChIKey
AKOYYWJWILIASW-NYYWCZLTSA-N
PubChem Compound ID
10336056
Target and Pathway
Target(s) 5-hydroxytryptamine 2C receptor Target Info Inhibitor [526321]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Gap junction
Serotonergic synapse
Inflammatory mediator regulation of TRP channels
PANTHER Pathway 5HT2 type receptor mediated signaling pathway
Reactome Serotonin receptors
G alpha (q) signalling events
WikiPathways Serotonin Receptor 2 and ELK-SRF/GATA4 signaling
Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 526321J Nat Prod. 2002 Apr;65(4):476-80.New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea.
Ref 526321J Nat Prod. 2002 Apr;65(4):476-80.New antiinfective and human 5-HT2 receptor binding natural and semisynthetic compounds from the Jamaican sponge Smenospongia aurea.

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