Drug General Information
Drug ID
D03NZW
Former ID
DIB020740
Drug Name
PMD38
Synonyms
p-menthane-3,8-diol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539599]
Structure
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2D MOL
Formula
C10H20O2
InChI
InChI=1S/C10H20O2/c1-7-4-5-8(9(11)6-7)10(2,3)12/h7-9,11-12H,4-6H2,1-3H3/t7-,8-,9-/m1/s1
InChIKey
LMXFTMYMHGYJEI-IWSPIJDZSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) TRPM8 protein Target Info Activator [526953]
KEGG Pathway Inflammatory mediator regulation of TRP channels
Reactome TRP channels
References
Ref 539599(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2472).
Ref 526953Characterization of the mouse cold-menthol receptor TRPM8 and vanilloid receptor type-1 VR1 using a fluorometric imaging plate reader (FLIPR) assay. Br J Pharmacol. 2004 Feb;141(4):737-45. Epub 2004Feb 2.

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