Drug General Information
Drug ID	D03RSA
Former ID	DNC013074
Drug Name	M6S
Indication	Discovery agent		Investigative	[528255]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Mu-type opioid receptor	Target Info	Inhibitor	[528255]
	Kappa-type opioid receptor	Target Info	Inhibitor	[528255]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Estrogen signaling pathway
	Morphine addictionhsa04080:Neuroactive ligand-receptor interaction
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Enkephalin releaseP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Opioid prodynorphin pathway
Pathway Interaction Database	IL4-mediated signaling events
Reactome	Peptide ligand-binding receptors
	G alpha (i) signalling eventsR-HSA-375276:Peptide ligand-binding receptors
	G alpha (i) signalling events
WikiPathways	TCR Signaling Pathway
	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	Opioid Signalling
	GPCR ligand binding
	GPCR downstream signalingWP455:GPCRs, Class A Rhodopsin-like
	GPCR downstream signaling
References
Ref 528255	Bioorg Med Chem Lett. 2006 Aug 15;16(16):4291-5. Epub 2006 Jun 13.Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners.
Ref 528255	Bioorg Med Chem Lett. 2006 Aug 15;16(16):4291-5. Epub 2006 Jun 13.Opiate receptor binding properties of morphine-, dihydromorphine-, and codeine 6-O-sulfate ester congeners.

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