Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D03VGO
|
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| Former ID |
DIB019949
|
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| Drug Name |
GSK2194069
|
||||
| Synonyms |
GSK-2194069; GSK 2194069
|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent | Investigative | [532905] | ||
| Structure |
|
Download2D MOL |
|||
| Formula |
C25H24N4O3
|
||||
| InChI |
InChI=1S/C25H24N4O3/c30-24(18-1-2-18)28-11-9-16(15-28)13-23-26-27-25(31)29(23)21-6-3-17(4-7-21)19-5-8-22-20(14-19)10-12-32-22/h3-8,10,12,14,16,18H,1-2,9,11,13,15H2,(H,27,31)/t16-/m0/s1
|
||||
| InChIKey |
AQTPWCUIYUOEMG-INIZCTEOSA-N
|
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| PubChem Compound ID | |||||
| PubChem Substance ID | |||||
| Target and Pathway | |||||
| Target(s) | Fatty acid synthase | Target Info | Inhibitor | [532905] | |
| Pathway Interaction Database | p73 transcription factor network | ||||
| Validated transcriptional targets of deltaNp63 isoforms | |||||
| PathWhiz Pathway | Fatty Acid Biosynthesis | ||||
| WikiPathways | Fatty Acid Biosynthesis | ||||
| Nuclear Receptors Meta-Pathway | |||||
| Liver X Receptor Pathway | |||||
| Activation of Gene Expression by SREBP (SREBF) | |||||
| SREBF and miR33 in cholesterol and lipid homeostasis | |||||
| SREBP signalling | |||||
| Metabolism of water-soluble vitamins and cofactors | |||||
| Integration of energy metabolism | |||||
| Fatty acid, triacylglycerol, and ketone body metabolism | |||||
| AMPK Signaling | |||||
| References | |||||
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