Drug Information

Drug General Information
Drug ID
D03VPC
Former ID
DAP000191
Drug Name
Cilostazol
Synonyms
Cilostazole; Cilostazolum; Pletaal; Pletal; Otsuka brand of cilostazol; C 0737; CL23867; OPC 13013; OPC 21; Cilostazol [INN:JAN]; Cilostazolum [INN-Latin]; OPC-13013; OPC-21; Pleta (TN); Pletal (TN); Pletal, Cilostazol; Cilostazol (JP15/USAN/INN); 3,4-Dihydro-6-(4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy)-2(1H)-quinolinone; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydro-2(1H)-quinolinone; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxy)-3,4-dihydrocarbostyril; 6-(4-(1-Cyclohexyl-1H-tetrazol-5-yl)butoxyl)-3,4-dihydrocarobostyril; 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-2(1H)-quinolinone; 6-[4-(1-cyclohexyl-1H-tetrazol-5-yl)butoxy]-3,4-dihydroquinolin-2(1H)-one; 6-[4-(1-cyclohexyltetrazol-5-yl)butoxy]-3,4-dihydro-1H-quinolin-2-one
Drug Type
Small molecular drug
Indication Intermittent claudication [ICD9: 440.21; ICD10:I73.9] Approved [536186], [542155]
Therapeutic Class
Vasodilator Agents
Company
Otsuka Pharmaceutical Co
Structure
Download
2D MOL

3D MOL
Formula
C20H27N5O2
InChI
InChI=1S/C20H27N5O2/c26-20-12-9-15-14-17(10-11-18(15)21-20)27-13-5-4-8-19-22-23-24-25(19)16-6-2-1-3-7-16/h10-11,14,16H,1-9,12-13H2,(H,21,26)
InChIKey
RRGUKTPIGVIEKM-UHFFFAOYSA-N
CAS Number
CAS 73963-72-1
PubChem Compound ID
2754
PubChem Substance ID
855683, 6897916, 7848958, 7978527, 8151779, 11110906, 11113335, 11372358, 11374323, 11484992, 11488934, 11490985, 11492587, 11528739, 12012700, 14755273, 14828756, 17404781, 24278291, 26612838, 26680450, 26719653, 26719654, 26746958, 26746959, 29221909, 46386747, 46386994, 46506317, 47365365, 48259412, 48259413, 49834949, 50100194, 50103999, 50104000, 50409718, 53777324, 53787948, 56422089, 56463107, 57321435, 68530811, 85230957, 85787626, 87218800, 87218801, 87219014, 90341176, 92124839
SuperDrug ATC ID
B01AC23
Target and Pathway
Target(s) Phosphodiesterase (PDE) 3 Target Info Modulator [556264]
References
Ref 536186Emerging drugs in peripheral arterial disease. Expert Opin Emerg Drugs. 2006 Mar;11(1):75-90.
Ref 542155(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 7148).
Ref 556264Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services.

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