TTD | Drug: D03WIK

Drug General Information
Drug ID	D03WIK
Former ID	DIB018569
Drug Name	2-O-ethyl-PAF C-16
Synonyms	2-O-ethyl-platelet-activating factor C-16
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[539137]
Structure		Download 2D MOL
Formula	C26H57NO6P+
InChI	InChI=1S/C26H56NO6P/c1-6-8-9-10-11-12-13-14-15-16-17-18-19-20-22-30-24-26(31-7-2)25-33-34(28,29)32-23-21-27(3,4)5/h26H,6-25H2,1-5H3/p+1
InChIKey	LPHUUVMLQFHHQG-UHFFFAOYSA-O
PubChem Compound ID	9546625
PubChem Substance ID	78883002, 135651397
Target and Pathway
Target(s)	Platelet-activating factor receptor	Target Info	Agonist	[533649]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Staphylococcus aureus infection
NetPath Pathway	IL5 Signaling Pathway
NetPath Pathway	Leptin Signaling Pathway
Reactome	Class A/1 (Rhodopsin-like receptors)
	G alpha (q) signalling events
	Interferon gamma signaling
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Small Ligand GPCRs
	Interferon gamma signaling
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 539137	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1829).
Ref 533649	A radioreceptor binding assay for platelet-activating factor (PAF) using membranes from CHO cells expressing human PAF receptor. J Immunol Methods. 1995 Oct 26;186(2):225-31.

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Drug Information