Drug General Information
Drug ID	D03XKU
Former ID	DNC008148
Drug Name	4-ethyl-3,4-dihydroquinazolin-2-amine
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[529148]
Structure		Download 2D MOL 3D MOL
Formula	C10H13N3
Canonical SMILES	CCC1C2=CC=CC=C2NC(=N1)N
InChI	1S/C10H13N3/c1-2-8-7-5-3-4-6-9(7)13-10(11)12-8/h3-6,8H,2H2,1H3,(H3,11,12,13)
InChIKey	FUFWGLRRMNVLPD-UHFFFAOYSA-N
PubChem Compound ID	44455986
Target and Pathway
Target(s)	5-hydroxytryptamine 5A receptor	Target Info	Inhibitor	[529148]
KEGG Pathway	Calcium signaling pathway
	Neuroactive ligand-receptor interaction
	Serotonergic synapse
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome	Serotonin receptors
	G alpha (i) signalling events
WikiPathways	Monoamine GPCRs
	GPCRs, Class A Rhodopsin-like
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 529148	Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.
Ref 529148	Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.