TTD | Drug: D03ZDC

Drug General Information
Drug ID	D03ZDC
Former ID	DNC001003
Drug Name	NE21650
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[540151]
Structure		Download 2D MOL 3D MOL
Formula	C8H13NO7P2
InChI	InChI=1S/C8H13NO7P2/c9-7-4-2-1-3-6(7)5-8(10,17(11,12)13)18(14,15)16/h1-4,10H,5,9H2,(H2,11,12,13)(H2,14,15,16)
InChIKey	VJXYJONFUZXZJZ-UHFFFAOYSA-N
CAS Number	CAS 169758-66-1
PubChem Compound ID	9994754
PubChem Substance ID	14973931, 24253749, 26683781, 44046075, 57373974, 78568102, 103470386, 104059656, 135650699, 247803854
Target and Pathway
Target(s)	Farnesyl pyrophosphatesynthetase	Target Info	Inhibitor	[535340]
KEGG Pathway	Terpenoid backbone biosynthesis
	Metabolic pathways
	Biosynthesis of antibiotics
	Influenza A
	HTLV-I infection
PathWhiz Pathway	Steroid Biosynthesis
Reactome	Cholesterol biosynthesis
Reactome	Activation of gene expression by SREBF (SREBP)
WikiPathways	Activation of Gene Expression by SREBP (SREBF)
	SREBP signalling
	Cholesterol Biosynthesis
References
Ref 540151	(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 3167).
Ref 535340	Identification of a bisphosphonate that inhibits isopentenyl diphosphate isomerase and farnesyl diphosphate synthase. Biochem Biophys Res Commun. 2002 Jan 18;290(2):869-73.

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Drug Information