Drug Information

Drug General Information
Drug ID
D04AXY
Former ID
DNC012608
Drug Name
6-(4-Methyl-piperazin-1-yl)-phenanthridine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [525484]
Structure
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2D MOL

3D MOL
Formula
C18H19N3
Canonical SMILES
CN1CCN(CC1)C2=NC3=CC=CC=C3C4=CC=CC=C42
InChI
1S/C18H19N3/c1-20-10-12-21(13-11-20)18-16-8-3-2-6-14(16)15-7-4-5-9-17(15)19-18/h2-9H,10-13H2,1H3
InChIKey
ZVJIBTNUNUXAIO-UHFFFAOYSA-N
PubChem Compound ID
9993659
Target and Pathway
Target(s) 5-hydroxytryptamine receptor 3A Target Info Inhibitor [525484]
5-hydroxy-tryptamine 3B receptor Target Info Inhibitor [525484]
KEGG Pathway Serotonergic synapsehsa04726:Serotonergic synapse
NetPath Pathway IL2 Signaling Pathway
PANTHER Pathway 5HT3 type receptor mediated signaling pathwayP04375:5HT3 type receptor mediated signaling pathway
Reactome Ligand-gated ion channel transportR-HSA-975298:Ligand-gated ion channel transport
WikiPathways SIDS Susceptibility Pathways
Iron uptake and transportWP2670:Iron uptake and transport
References
Ref 525484J Med Chem. 1999 May 6;42(9):1556-75.Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.
Ref 525484J Med Chem. 1999 May 6;42(9):1556-75.Novel potent and selective central 5-HT3 receptor ligands provided with different intrinsic efficacy. 2. Molecular basis of the intrinsic efficacy of arylpiperazine derivatives at the central 5-HT3 receptors.

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