Drug Information

Drug General Information
Drug ID
D04EYR
Former ID
DNC000942
Drug Name
Metrenperone
Drug Type
Small molecular drug
Indication Discovery agent Investigative [534838], [537926], [537928], [537935]
Structure
Download
2D MOL

3D MOL
Formula
C24H26FN3O2
Canonical SMILES
CC1=CN2C(=NC(=C(C2=O)CCN3CCC(CC3)C(=O)C4=CC=C(C=C4)F)C)<br />C=C1
InChI
1S/C24H26FN3O2/c1-16-3-8-22-26-17(2)21(24(30)28(22)15-16)11-14-27-12-9-19(10-13-27)23(29)18-4-6-20(25)7-5-18/h3-8,15,19H,9-14H2,1-2H3
InChIKey
AXQRPYKSPHUOGZ-UHFFFAOYSA-N
CAS Number
CAS 81043-56-3
PubChem Compound ID
72005
PubChem Substance ID
8194961, 15500250, 43128243, 47206742, 57318476, 76940097, 103830962, 104351853, 117509571, 127473869, 134338782, 134340225, 135029640, 136350354, 137263795, 138332609, 160703411, 164230510, 179294166, 198978668, 228248735, 241162488
Target and Pathway
Target(s) 5-hydroxytryptamine 2 receptor Target Info Antagonist [534838], [537926], [537928], [537935]
References
Ref 534838Cardiovascular response to intravenous administration of 5-hydroxytryptamine after type-2 receptor blockade, by metrenperone, in healthy calves. Vet J. 1999 Jan;157(1):31-7.
Ref 537926Efficiency of 5-hydroxytryptamine receptor blockade as therapeutic measure during acute respiratory distress syndrome in double-muscled cattle. Zentralbl Veterinarmed A. 1993 Apr;40(3):185-93.
Ref 537928Induction of serotonin-S2 receptor blockade during early or late stage of acute respiratory distress syndrome in double-muscled calves: a comparative study. Zentralbl Veterinarmed A. 1993 May;40(4):241-8.
Ref 537935Pulmonary response to intravenous administration of 5-hydroxytryptamine after type-2 receptor blockade in healthy calves. Am J Vet Res. 1993 Jan;54(1):168-73.
Ref 534838Cardiovascular response to intravenous administration of 5-hydroxytryptamine after type-2 receptor blockade, by metrenperone, in healthy calves. Vet J. 1999 Jan;157(1):31-7.
Ref 537926Efficiency of 5-hydroxytryptamine receptor blockade as therapeutic measure during acute respiratory distress syndrome in double-muscled cattle. Zentralbl Veterinarmed A. 1993 Apr;40(3):185-93.
Ref 537928Induction of serotonin-S2 receptor blockade during early or late stage of acute respiratory distress syndrome in double-muscled calves: a comparative study. Zentralbl Veterinarmed A. 1993 May;40(4):241-8.
Ref 537935Pulmonary response to intravenous administration of 5-hydroxytryptamine after type-2 receptor blockade in healthy calves. Am J Vet Res. 1993 Jan;54(1):168-73.

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