Drug General Information
Drug ID
D04IFV
Former ID
DNC011769
Drug Name
5-Methyl-2-p-tolyl-thiazol-4-ol
Drug Type
Small molecular drug
Indication Discovery agent Investigative [531065]
Structure
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2D MOL

3D MOL

Formula
C11H11NOS
Canonical SMILES
CC1=CC=C(C=C1)C2=NC(=C(S2)C)O
InChI
1S/C11H11NOS/c1-7-3-5-9(6-4-7)11-12-10(13)8(2)14-11/h3-6,13H,1-2H3
InChIKey
CKXYNXQZWQQOOO-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) Arachidonate 5-lipoxygenase Target Info Inhibitor [531065]
BioCyc Pathway Aspirin-triggered lipoxin biosynthesis
Resolvin D biosynthesis
Leukotriene biosynthesis
Lipoxin biosynthesis
Aspirin triggered resolvin D biosynthesis
Aspirin triggered resolvin E biosynthesis
KEGG Pathway Arachidonic acid metabolism
Metabolic pathways
Serotonergic synapse
Ovarian steroidogenesis
Toxoplasmosis
NetPath Pathway IL4 Signaling Pathway
PathWhiz Pathway Arachidonic Acid Metabolism
WikiPathways Vitamin D Receptor Pathway
Arachidonic acid metabolism
Eicosanoid Synthesis
Selenium Micronutrient Network
References
Ref 531065J Med Chem. 1991 Jul;34(7):2158-65.4-hydroxythiazole inhibitors of 5-lipoxygenase.
Ref 531065J Med Chem. 1991 Jul;34(7):2158-65.4-hydroxythiazole inhibitors of 5-lipoxygenase.

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