Drug Information

Drug General Information
Drug ID
D04JCJ
Former ID
DNC007800
Drug Name
6-(4-(2-(benzylamino)ethyl)phenoxy)picolinamide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [528996]
Structure
Download
2D MOL

3D MOL
Formula
C21H21N3O2
Canonical SMILES
C1=CC=C(C=C1)CNCCC2=CC=C(C=C2)OC3=CC=CC(=N3)C(=O)N
InChI
1S/C21H21N3O2/c22-21(25)19-7-4-8-20(24-19)26-18-11-9-16(10-12-18)13-14-23-15-17-5-2-1-3-6-17/h1-12,23H,13-15H2,(H2,22,25)
InChIKey
JKDWSAGAQLISRL-UHFFFAOYSA-N
PubChem Compound ID
44434931
Target and Pathway
Target(s) Mu-type opioid receptor Target Info Inhibitor [528996]
KEGG Pathway Neuroactive ligand-receptor interaction
Estrogen signaling pathway
Morphine addiction
NetPath Pathway TCR Signaling Pathway
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
Enkephalin release
Pathway Interaction Database IL4-mediated signaling events
Reactome Peptide ligand-binding receptors
G alpha (i) signalling events
WikiPathways TCR Signaling Pathway
GPCRs, Class A Rhodopsin-like
Peptide GPCRs
Opioid Signalling
GPCR ligand binding
GPCR downstream signaling
References
Ref 528996Bioorg Med Chem Lett. 2007 Oct 1;17(19):5349-52. Epub 2007 Aug 11.Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.
Ref 528996Bioorg Med Chem Lett. 2007 Oct 1;17(19):5349-52. Epub 2007 Aug 11.Structure-activity relationship studies of carboxamido-biaryl ethers as opioid receptor antagonists (OpRAs). Part 1.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.