Drug General Information
Drug ID	D04JJE
Former ID	DIB007034
Drug Name	RP-66153
Drug Type	Small molecular drug
Indication	Asthma [ICD10:J45]		Terminated	[545628]
Company	Rhone-Poulenc SA
Structure		Download 2D MOL 3D MOL
Formula	C22H30O2S
Canonical SMILES	c1(c(ccs1)CCCc1ccccc1)CCCCCC(C(=O)O)(C)C
CAS Number	CAS 142422-79-5
PubChem Compound ID	132425
Target and Pathway
Target(s)	Leukotriene B4 receptor 1	Target Info	Modulator	[526746]
KEGG Pathway	Neuroactive ligand-receptor interaction
NetPath Pathway	IL4 Signaling Pathway
Reactome	Leukotriene receptors
	G alpha (q) signalling events
WikiPathways	Nucleotide GPCRs
	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	Spinal Cord Injury
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 545628	Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003980)
Ref 526746	Omega-[(omega-arylalkyl)thienyl]alkanoic acids: from specific LTA4 hydrolase inhibitors to LTB4 receptor antagonists. J Med Chem. 1992 Aug 21;35(17):3170-9.

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