Drug Information

Drug General Information
Drug ID
D04MRV
Former ID
DNC000199
Drug Name
Amifloxacin
Drug Type
Small molecular drug
Indication Discovery agent Discontinued in Phase 2 [544658]
Structure
Download
2D MOL

3D MOL
Formula
C16H19FN4O3
Canonical SMILES
CNN1C=C(C(=O)C2=CC(=C(C=C21)N3CCN(CC3)C)F)C(=O)O
InChI
1S/C16H19FN4O3/c1-18-21-9-11(16(23)24)15(22)10-7-12(17)14(8-13(10)21)20-5-3-19(2)4-6-20/h7-9,18H,3-6H2,1-2H3,(H,23,24)
InChIKey
RUXPNBWPIRDVTH-UHFFFAOYSA-N
CAS Number
CAS 86393-37-5
PubChem Compound ID
55492
PubChem Substance ID
602915, 7978683, 8184165, 12012921, 14826857, 17397059, 43113463, 50663231, 57313763, 103163900, 104307744, 129185455, 134339701, 135014224, 137263422, 138063967, 140684356, 162725806, 179151330, 198954300, 224859229, 226431948
Target and Pathway
Target(s) DNA topoisomerase II Target Info Inhibitor [537698]
References
Ref 544658Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000457)
Ref 537698Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro. Antimicrob Agents Chemother. 1988 Aug;32(8):1182-6.

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