Drug Information

Drug General Information
Drug ID
D04MSM
Former ID
DIB013444
Drug Name
Carbamazepine
Synonyms
Carbamazepine (iv, epilepsy); Carbamazepine (iv, epilepsy), Lundbeck; Carbamazepine (iv, epilepsy), Ovation Pharmaceuticals
Drug Type
Small molecular drug
Indication Epilepsy [ICD10:G40] Approved [528598], [540778]
Company
Lundbeck Inc
Structure
Download
2D MOL

3D MOL
Formula
C15H12N2O
InChI
InChI=1S/C15H12N2O/c16-15(18)17-13-7-3-1-5-11(13)9-10-12-6-2-4-8-14(12)17/h1-10H,(H2,16,18)
InChIKey
FFGPTBGBLSHEPO-UHFFFAOYSA-N
PubChem Compound ID
2554
PubChem Substance ID
9085, 442467, 621391, 855967, 866528, 3154113, 5051955, 7847318, 7978855, 8149231, 8151689, 10321205, 10517602, 11109646, 11110939, 11110940, 11207111, 11335563, 11338925, 11360802, 11362930, 11365492, 11368054, 11371249, 11373863, 11376216, 11461774, 11466080, 11467200, 11483906, 11485860, 11487941, 11490141, 11492077, 11493910, 11514284, 14847331, 17389547, 17404855, 24278084, 24893120, 26611636, 26679702, 26747063, 26747064, 26751576, 29221715, 46507583, 47216705, 47365117
Target and Pathway
Target(s) Sodium channel Target Info Modulator [532579]
KEGG Pathway Dopaminergic synapse
Reactome Interaction between L1 and Ankyrins
References
Ref 528598Thirty years of clinical experience with carbamazepine in the treatment of bipolar illness: principles and practice. CNS Drugs. 2007;21(1):47-71.
Ref 540778(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5339).
Ref 532579Sidedness of carbamazepine accessibility to voltage-gated sodium channels. Mol Pharmacol. 2014 Feb;85(2):381-7.

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