Drug General Information
Drug ID
D04TPA
Former ID
DIB019306
Drug Name
compound 1a
Drug Type
Small molecular drug
Indication Discovery agent Investigative [532826]
Structure
Download
2D MOL
Formula
C19H19N7O
InChI
InChI=1S/C19H19N7O/c1-11-3-4-15(7-16(11)22-12(2)27)23-17-8-18(24-14-5-6-14)26-19(25-17)13(9-20)10-21-26/h3-4,7-8,10,14,24H,5-6H2,1-2H3,(H,22,27)(H,23,25)
InChIKey
GDSQVLMYYCNAGP-UHFFFAOYSA-N
PubChem Compound ID
PubChem Substance ID
Target and Pathway
Target(s) Casein kinase II, alpha chain Target Info Inhibitor [532826]
PIM-3 protein kinase Target Info Inhibitor [532826]
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 Target Info Inhibitor [532826]
homeodomain interacting protein kinase 2 Target Info Inhibitor [532826]
KEGG Pathway Ribosome biogenesis in eukaryotes
NF-kappa B signaling pathway
Wnt signaling pathway
Adherens junction
Tight junction
Measles
Herpes simplex infection
Epstein-Barr virus infection
NetPath Pathway FSH Signaling Pathway
Pathway Interaction Database BCR signaling pathway
Atypical NF-kappaB pathway
DNA-PK pathway in nonhomologous end joining
Presenilin action in Notch and Wnt signaling
Role of Calcineurin-dependent NFAT signaling in lymphocytes
E-cadherin signaling in the nascent adherens junction
Lissencephaly gene (LIS1) in neuronal migration and development
PDGFR-alpha signaling pathway
Signaling mediated by p38-alpha and p38-beta
Alpha-synuclein signaling
Reactome Condensation of Prometaphase Chromosomes
WikiPathways Mitotic Prometaphase
BDNF signaling pathway
TNF alpha Signaling Pathway
L1CAM interactions
References
Ref 532826Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo. ACS Med Chem Lett. 2013 Jul 3;4(8):800-5.
Ref 532826Structure and Property Based Design of Pyrazolo[1,5-a]pyrimidine Inhibitors of CK2 Kinase with Activity in Vivo. ACS Med Chem Lett. 2013 Jul 3;4(8):800-5.

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