Drug Information
| Drug General Information | |||||
|---|---|---|---|---|---|
| Drug ID |
D04TTN
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| Former ID |
DNC013743
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| Drug Name |
(+)-(1R,1'S)-thaligrisine hydrochloride
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent | Investigative | [551356] | ||
| Structure |
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Download2D MOL |
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| Formula |
C37H43ClN2O6
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| Canonical SMILES |
CN1CCC2=CC(=C(C=C2C1CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC5C6=<br />CC(=C(C=C6CCN5C)OC)O)OC)O)OC.Cl
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| InChI |
1S/C37H42N2O6.ClH/c1-38-14-12-25-19-35(43-4)32(40)21-28(25)30(38)16-23-6-9-27(10-7-23)45-37-18-24(8-11-34(37)42-3)17-31-29-22-33(41)36(44-5)20-26(29)13-15-39(31)2;/h6-11,18-22,30-31,40-41H,12-17H2,1-5H3;1H/t30-,31+;/m0./s1
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| InChIKey |
NSNGMSCZFBHCEX-LBYXUWKHSA-N
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| PubChem Compound ID | |||||
| Target and Pathway | |||||
| Target(s) | Dopamine D1 receptor | Target Info | Inhibitor | [551356] | |
| D(2) dopamine receptor | Target Info | Inhibitor | [551356] | ||
| PANTHER Pathway | Dopamine receptor mediated signaling pathwayP00026:Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway | ||||
| Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway | |||||
| Dopamine receptor mediated signaling pathway | |||||
| Nicotine pharmacodynamics pathway | |||||
| PathWhiz Pathway | Dopamine Activation of Neurological Reward System | ||||
| WikiPathways | Hypothetical Network for Drug Addiction | ||||
| Monoamine GPCRs | |||||
| GPCRs, Class A Rhodopsin-like | |||||
| Genes and (Common) Pathways Underlying Drug Addiction | |||||
| GPCR ligand binding | |||||
| GPCR downstream signalingWP666:Hypothetical Network for Drug Addiction | |||||
| GPCR downstream signaling | |||||
| Nicotine Activity on Dopaminergic Neurons | |||||
| References | |||||
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