TTD | Drug: D04TZR

Drug General Information
Drug ID	D04TZR
Drug Name	ICI-204448
Synonyms	121264-04-8; ICI-204448
Drug Type	Small molecular drug
Indication	Unspecified		Investigative	[1560458]
Structure		Download 2D MOL 3D MOL
Formula	C23H26Cl2N2O4
PubChem Compound ID	3683
Target and Pathway
Target(s)	Kappa-type opioid receptor	Target Info	Modulator
KEGG Pathway	Neuroactive ligand-receptor interaction
PANTHER Pathway	Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
	Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway
	Opioid prodynorphin pathway
Reactome	Peptide ligand-binding receptors
Reactome	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Peptide GPCRs
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 1560458	ICI 204448: a kappa-opioid agonist with limited access to the CNS.

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Drug Information