Drug Information

Drug General Information
Drug ID
D04UHT
Former ID
DIB021140
Drug Name
urotensin II-related peptide
Synonyms
urotensin-related peptide
Drug Type
Small molecular drug
Indication Discovery agent Investigative [539368]
Structure
Download
2D MOL
Formula
C49H70N10O10S2
InChI
InChI=1S/C49H70N10O10S2/c1-27(2)41(49(68)69)59-48(67)40-26-71-70-25-39(57-42(61)28(3)51)47(66)55-36(21-29-11-5-4-6-12-29)44(63)56-38(23-31-24-52-34-14-8-7-13-33(31)34)46(65)53-35(15-9-10-20-50)43(62)54-37(45(64)58-40)22-30-16-18-32(60)19-17-30/h7-8,13-14,16-19,24,27-29,35-41,52,60H,4-6,9-12,15,20-23,25-26,50-51H2,1-3H3,(H,53,65)(H,54,62)(H,55,66)(H,56,63)(H,57,61)(H,58,64)(H,59,67)(H,68,69)/t28-,35-,36-,37-,38-,39-,40-,41-/m0/s1
InChIKey
BKBNRUZZGBUWOM-KOOAXUMWSA-N
PubChem Compound ID
11995575
PubChem Substance ID
17494707, 26547602, 37443954, 77315567, 103501569, 103916898, 135651910
Target and Pathway
Target(s) Urotensin II receptor Target Info Agonist [526843]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
WikiPathways Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
GPCRs, Other
References
Ref 539368(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2156).
Ref 526843Identification of urotensin II-related peptide as the urotensin II-immunoreactive molecule in the rat brain. Biochem Biophys Res Commun. 2003 Oct 24;310(3):860-8.

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