Drug General Information
Drug ID
D04UTQ
Former ID
DNC008146
Drug Name
N,N-dimethyl-3,4-dihydroquinazolin-2-amine
Drug Type
Small molecular drug
Indication Discovery agent Investigative [529148]
Structure
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2D MOL

3D MOL

Formula
C10H13N3
Canonical SMILES
CN(C)C1=NCC2=CC=CC=C2N1
InChI
1S/C10H13N3/c1-13(2)10-11-7-8-5-3-4-6-9(8)12-10/h3-6H,7H2,1-2H3,(H,11,12)
InChIKey
MNTBAXGKERZVOZ-UHFFFAOYSA-N
PubChem Compound ID
Target and Pathway
Target(s) 5-hydroxytryptamine 5A receptor Target Info Inhibitor [529148]
KEGG Pathway Calcium signaling pathway
Neuroactive ligand-receptor interaction
Serotonergic synapse
PANTHER Pathway Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway
Reactome Serotonin receptors
G alpha (i) signalling events
WikiPathways Monoamine GPCRs
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 529148Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.
Ref 529148Bioorg Med Chem Lett. 2008 Jan 1;18(1):256-61. Epub 2007 Oct 30.Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: structure-activity relationship elucidation.

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