Drug General Information
Drug ID	D04UUT
Former ID	DNC011958
Drug Name	2-Furan-2-yl-6H-pyrazolo[1,5-c]quinazolin-5-one
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[534157]
Structure		Download 2D MOL 3D MOL
Formula	C14H9N3O2
Canonical SMILES	C1=CC2=C3C=C(NN3C(=O)N=C2C=C1)C4=CC=CO4
InChI	1S/C14H9N3O2/c18-14-15-10-5-2-1-4-9(10)12-8-11(16-17(12)14)13-6-3-7-19-13/h1-8,16H
InChIKey	CURSNYMOHJSYQS-UHFFFAOYSA-N
PubChem Compound ID	10467327
Target and Pathway
Target(s)	Gamma-aminobutyric acid receptor	Target Info	Inhibitor	[534157]
	Gamma-aminobutyric acid receptor subunit alpha-1	Target Info	Inhibitor	[534157]
KEGG Pathway	Neuroactive ligand-receptor interaction
	Retrograde endocannabinoid signaling
	GABAergic synapse
	Morphine addiction
	Nicotine addiction
Reactome	Ligand-gated ion channel transport
	GABA A receptor activation
WikiPathways	SIDS Susceptibility Pathways
	Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
	Iron uptake and transport
References
Ref 534157	J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.
Ref 534157	J Med Chem. 1996 Jul 19;39(15):2915-21.Synthesis and binding activity of some pyrazolo[1,5-c]quinazolines as tools to verify an optional binding site of a benzodiazepine receptor ligand.

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