Drug General Information
Drug ID	D04VNR
Former ID	DNC012787
Drug Name	2-Naphthalen-2-ylmethyl-4,5-dihydro-1H-imidazole
Drug Type	Small molecular drug
Indication	Discovery agent		Investigative	[534352]
Structure		Download 2D MOL 3D MOL
Formula	C14H14N2
Canonical SMILES	C1CN=C(N1)CC2=CC3=CC=CC=C3C=C2
InChI	1S/C14H14N2/c1-2-4-13-9-11(5-6-12(13)3-1)10-14-15-7-8-16-14/h1-6,9H,7-8,10H2,(H,15,16)
InChIKey	VIXRKFBKWOHVBR-UHFFFAOYSA-N
PubChem Compound ID	610682
Target and Pathway
Target(s)	Sodium-dependent serotonin transporter	Target Info	Inhibitor	[534352]
KEGG Pathway	Serotonergic synapse
NetPath Pathway	TCR Signaling Pathway
PANTHER Pathway	5HT1 type receptor mediated signaling pathway
	5HT2 type receptor mediated signaling pathway
	5HT3 type receptor mediated signaling pathway
	5HT4 type receptor mediated signaling pathway
WikiPathways	Monoamine Transport
	SIDS Susceptibility Pathways
	NRF2 pathway
	Synaptic Vesicle Pathway
	Serotonin Transporter Activity
References
Ref 534352	J Med Chem. 1997 Mar 28;40(7):1049-62.Structure-activity studies for a novel series of N-(arylethyl)-N-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamine s possessing dual 5-HT uptake inhibitingand alpha2-antagonistic activities.
Ref 534352	J Med Chem. 1997 Mar 28;40(7):1049-62.Structure-activity studies for a novel series of N-(arylethyl)-N-(1,2,3,4-tetrahydronaphthalen-1-ylmethyl)-N-methylamine s possessing dual 5-HT uptake inhibitingand alpha2-antagonistic activities.

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