Drug Information

Drug General Information
Drug ID
D04WDX
Former ID
DNC001128
Drug Name
PJ34
Drug Type
Small molecular drug
Indication Discovery agent Investigative [535095]
Structure
Download
2D MOL

3D MOL
Formula
C17H17N3O2
Canonical SMILES
CN(C)CC(=O)NC1=CC2=C(C=C1)NC(=O)C3=CC=CC=C32
InChI
1S/C17H17N3O2/c1-20(2)10-16(21)18-11-7-8-15-14(9-11)12-5-3-4-6-13(12)17(22)19-15/h3-9H,10H2,1-2H3,(H,18,21)(H,19,22)
InChIKey
UYJZZVDLGDDTCL-UHFFFAOYSA-N
CAS Number
CAS 79775-19-2
PubChem Compound ID
4858
PubChem Substance ID
5005827, 6435849, 6435929, 7889674, 8152987, 14898161, 29223939, 46393562, 47211625, 49649993, 57299206, 57304736, 80903002, 85756513, 99444819, 103468748, 104307634, 126408013, 134352305, 142463587, 162511565, 170474817, 177748919, 178483466, 185990451, 210274932, 210280569, 211786747, 223401601, 223519286, 223749822, 226087992, 226747694, 248281898, 252255698, 252473119
Target and Pathway
Target(s) Poly [ADP-ribose] polymerase-1 Target Info Inhibitor [535095]
KEGG Pathway Base excision repair
NF-kappa B signaling pathway
PANTHER Pathway FAS signaling pathway
Pathway Interaction Database Integrin-linked kinase signaling
Caspase Cascade in Apoptosis
Notch-mediated HES/HEY network
Reactome Dual Incision in GG-NER
WikiPathways FAS pathway and Stress induction of HSP regulation
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
Nanoparticle triggered regulated necrosis
Corticotropin-releasing hormone
References
Ref 535095Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001 Jan;7(1):108-13.
Ref 535095Diabetic endothelial dysfunction: the role of poly(ADP-ribose) polymerase activation. Nat Med. 2001 Jan;7(1):108-13.

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